Inclusion Criteria

Inclusion criteria :

Patient sent in the service of Gastroenterology Pediatric Hepatology of the Hospital
Necker Enfants Malades for an intestinal transplantation, from 0 to 15 years old
presenting:

- A known epithelial dysplasia (Diagnosis established on the clinical and
histo-morphological criteria from one or several intestinal biopsies, with or without
diagnosis known or suspected in the family). The objectives are the phenotypic
characterization of the case and the revealing of markers characteristic
immuno-histochemistry which can be of use to the diagnosis and direct to candidate
genes

- Or a suspicion of dysplasia epithelial (compatible clinical History(Story) with or
without extra-digestive demonstrations(appearances) of type keratinate punctuated
superficial (KPS), abnormalities cutanea or atresia CHOANS with atypical digestive
histology and without diagnosis known in the family). The objectives are the
diagnosis on the basis of the immuno-histochemistry expression and the existence of
an infringement(achievement) conjunctival and the phenotypic characterization of the
case

- The lit(enlightened) and written consent of both holders of the parental authority
must be beforehand obtained as well as that of the patient if it is in age to
understand(include).

Exclusion criteria :

- Not membership in a national insurance scheme (beneficiary or legal successor)

- Family not understanding(including) French

- Refusal of one of both relatives(parents)