Know Cancer

forgot password

Increasing CRC Screening in Primary Care Settings

Phase 3
50 Years
Not Enrolling
Colorectal Cancer Screening

Thank you

Trial Information

Increasing CRC Screening in Primary Care Settings

Regular screening reduces both morbidity and mortality from colorectal cancer (CRC).
Screening rates, however, remain low suggesting the need for innovative research designed to
increase screening behavior. The purpose of this study is to compare the effectiveness of
two interventions (Tailored Health Communication [THC] and Motivational Interviewing [MI])
in increasing CRC screening behavior. Both interventions are based on a strong conceptual
framework derived from the Health Belief Model (HBM) and Transtheoretical Model (TTM),
allowing us to explore the underlying mechanisms through which these interventions impact
behavior change.

The primary aim of this study is to compare CRC screening test use among 804 participants
randomly allocated to control or intervention conditions; participants will be recruited
from the two sites (Chicago, IL, and Nashville, TN). The 3 study groups will receive (1)
standard care, (2) tailored health communication, and (3) motivational interviewing.
Eligibility criteria for study participants includes being 50 years or older, not having
CRC, and being of average or moderate risk for CRC. Study participants will be surveyed by
telephone about CRC-related beliefs pre-intervention (Time 1), 1 month postintervention
(Time 2), and at 6 months postintervention (Times 3 and 4, respectively). Dichotomous
behavioral outcomes (had screening test or not) and stages of CRC screening test adoption
(based on the TTM) will be assessed, as well as sociodemographic and belief predictors of
screening behavior. Binomial and multinomial logistic regression models will be used to
evaluate screening test use and stage of test adoption. Sociodemographic and belief
variables will be used as covariates, with intervention group as the primary independent
predictor. Descriptive statistics and ANOVA will be employed to assess between intervention
differences in amenable beliefs. Path (mediation) analysis will be performed to further
explore the underlying mechanisms through which THC and MI may differentially affect CRC
screening behavior.

Inclusion Criteria:

- all genders

- can speak, read, write English

- no diagnosis of colorectal cancer

- non-adherent with screening

- age 50 or older

Exclusion Criteria:

- had colorectal cancer

- adherent with screening

Type of Study:


Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Screening

Outcome Measure:

completing CRC screening test

Outcome Time Frame:

1 and 6 months post education

Safety Issue:


Principal Investigator

Usha Menon, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Arizona State University


United States: Institutional Review Board

Study ID:




Start Date:

October 2004

Completion Date:

January 2010

Related Keywords:

  • Colorectal Cancer Screening
  • colorectal cancer screening
  • tailored education
  • motivational interview
  • patient education
  • Colorectal Neoplasms