Inclusion Criteria:

- Solid tumor

- ECOG performance status 0-2

- Life expectancy greater than or equal to 12 weeks

- Must meet certain blood laboratory values

- Must meet criteria for time since the last dose of prior therapy

- Must provide written informed consent to participate in this study

Exclusion Criteria:

- Active and/or symptomatic brain tumors or brain metastases.

- Patients with unresolved nausea, vomiting, or diarrhea

- Any ongoing severe and/or uncontrolled medical condition that could compromise
participation in the study including heart, lung or inflammatory disease

- Any disease that may significantly alter the absorption of the study drug (for
example, ulcerative diseases, uncontrolled nausea, vomiting, diarrhea, malabsorption
syndrome, or removal of small bowel)

- Patients who are currently receiving treatment with steroids at a certain dose or
other immunosuppressive treatment that cannot be stopped prior to starting study drug

- Patients who are currently receiving treatment with certain medications

- Patients who have received radiation therapy or have undergone major surgery within
the last 4 weeks

- Women of child-bearing potential who are pregnant or breast feeding.

- Known diagnosis of human immunodeficiency virus (HIV) infection or chronic active
hepatitis B or C

- Patients unwilling or unable to follow the protocol

Other protocol-defined inclusion/exclusion criteria may apply