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Development of a Serum Proteomic Profile for Cervical Cancer With Potential Prognostic Value


N/A
N/A
N/A
Not Enrolling
Female
Cervical Cancer

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Trial Information

Development of a Serum Proteomic Profile for Cervical Cancer With Potential Prognostic Value


OBJECTIVES:

Primary

- To develop a serum proteomic profile for cervical cancer using banked pre-treatment
serum specimens from patients with invasive cervical cancer and to determine if this
serum proteomic profile has possible utility in cervical cancer prognosis.

Secondary

- To develop a serum proteomic profile for cervical cancer using banked post-treatment
serum specimens from these patients and to determine if this serum proteomic profile
has possible utility in cervical cancer prognosis.

OUTLINE: This is a multicenter study.

Banked serum specimens are used to generate proteomic profiles.

Inclusion Criteria


DISEASE CHARACTERISTICS:

- Histologically confirmed invasive adenocarcinoma, squamous cell carcinoma, or
adenosquamous cell carcinoma of the cervix

- Stage IIB, III, or IVA disease

- Eligible and evaluable for GOG-0191

- Pre- and/or post-treatment serum specimens available for proteomic analysis

PATIENT CHARACTERISTICS:

- Patient has given consent to allow their specimen(s) to be used for future cancer
research

PRIOR CONCURRENT THERAPY:

- See Disease Characteristics

Type of Study:

Observational

Study Design:

N/A

Outcome Measure:

Generation of a serum proteomic profile using banked pre-treatment serum specimens that may have potential utility for cervical cancer prognosis (overall survival and progression-free survival [PFS])

Safety Issue:

No

Principal Investigator

Samir N. Khleif, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

National Cancer Institute (NCI)

Authority:

Unspecified

Study ID:

CDR0000665346

NCT ID:

NCT01074424

Start Date:

February 2010

Completion Date:

Related Keywords:

  • Cervical Cancer
  • stage IIB cervical cancer
  • stage III cervical cancer
  • stage IVA cervical cancer
  • cervical adenocarcinoma
  • cervical adenosquamous cell carcinoma
  • cervical squamous cell carcinoma
  • Uterine Cervical Neoplasms

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