Inclusion Criteria:

- Patients with histologically confirmed Ib~IIa （FIGO）cervical carcinoma without
previous treatments

- Age between 18-70

- With the presence of these three pathological risk factors after radical surgery:(1)
positive lymphatic vascular space,(2)outer one-third invasion of the cervical stroma,
(3) bulky tumor≥4cm

- At least 3 months of disease-free survival

Exclusion Criteria:

- The presence of other uncontrolled life-threatening disease (Suffering from
myocardial infarction or stroke, or unstable angina, decompensated heart failure, or
a history of deep vein thrombosis)

- Receiving other anti-cancer therapy, such as traditional Chinese drug

- Don't be able to finish the whole treatment(chemotherapy or radiotherapy)

- liver dysfunction (ALT、AST>2.5×ULN)

- renal dysfunction (Creatinine>1.5×ULN)

- WBC<4,000/mm3 or PLT<100,000/mm3

- Received preoperative radiotherapy