Effects of Lutein Supplementation on Oxidative Stress and Inflammation in Healthy Nonsmokers
20 Years
80 Years
Both
Oxidative Stress in Healthy Subjects
Trial Information
Effects of Lutein Supplementation on Oxidative Stress and Inflammation in Healthy Nonsmokers
Participants with a history of smoking, alcohol consumption, body mass index (BMI)≥30kg/m2,
allergies, ocular diseases and participants taking vitamins or other food supplements
containing lutein were excluded from the study.
Inclusion Criteria:
- Healthy adult subjects aged in the range of 20 to 80
Exclusion Criteria:
- Participants with a history of smoking
- Alcohol consumption
- Body mass index (BMI)≥30kg/m2
- Allergies
- Ocular diseases or recent infections(within the last year) and participants taking
vitamins or other food supplements containing lutein the previous 2 months.
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Outcome Measure:
Biomarkers of lipid, protein and DNA oxidative damage, marker of antioxidant capacity and antioxidant enzyme activities(GPx,SOD and CAT)in healthy subjects.
Outcome Time Frame:
12 weeks
Safety Issue:
Yes
Authority:
China:the Fundamental Research Funds for the Central Universities, The medical ethics committee of Xi'an Jiaotong University College of MedicineUnited States: Food and Drug Administration
Study ID:
CNS-06094
NCT ID:
NCT01056094
Start Date:
April 2010
Completion Date:
August 2012
Related Keywords:
- Oxidative Stress in Healthy Subjects
- Inflammation
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