Inclusion Criteria:

- Immunocompromised patients with neutropenic fever who have been treated with
itraconazole oral solution as prophylaxis

- Female patients who are postmenopausal or received contraceptive operation or refrain
from sexual relations. Women of childbearing potential should conduct an effective
method of birth control (oral contraceptives, injections, intrauterine device, double
barrier method, contraceptive patch and male partner's sterilization) before
participation and during the study

- Male patients who will not have a baby within 2 months after the completion of
itraconazole therapy

Exclusion Criteria:

- Fever due to documented deep-seated fungal infection at the entry into the study, but
documented candidemia will be included

- Patients with kidney function abnormalities with calculated creatinine clearance of
30mL/min or lower

- Aminotransferase level > 5 X Upper Limit of Normal and total bilirubin level > 5
mL/dL due to hepatic dysfunction