Inclusion Criteria:

- Subjects diagnosed with Stage IIIB or IV breast cancer who have failed with or refuse
to receive standard chemotherapies

- Subjects with the expression of ER/PR negative; or positive ER/PR expression but have
failed with or refuse to receive hormonal therapy

- Either + or - expression of HER-2/neu gene

- ECOG status = 0-2

- At least have 1 evaluable and measurable metastatic lesion as defined by RECIST
criteria

- Adequate haematological, liver, and renal function

- At least 3 weeks has elapsed since prior chemotherapy, radiotherapy,
biological/hormonal therapy

- At least 4 weeks has elapsed since surgical biopsy / major surgery

Exclusion Criteria:

- Allergic to the trial product

- Any other disease state, including infections or uncontrolled illnesses that could
interfere with trial participation or trial evaluation

- Concurrent herbal (alternative) medicine or food supplements suspected to have effect
on cancer disease