Analytical Transversal Study of Cytokines Serum Levels in Chronic Low Back Pain Due to Herniated Disk
23 patients with at least three months of back pain due to herniated disk disease were
selected Diagnosis was confirmed by magnetic resonance imaging (MRI) or computerized
tomography (CT) imaging of the spine for all patients. In addition, pain severity had to be
³ 5 points on the Numerical Rating Scale (NRS) ranging from zero (no pain) to 10 (worst
imaginable pain).
The exclusion criteria were defined as one or more of the following: psychiatric disorders,
systemic or inflammatory disease, history of allergy, presence of motor deficits, history of
blood dyscrasia, pregnancy, active infection, tumor, use of analgesic drugs in the week
before or inability to come to the hospital for evaluation.
Interventional
Endpoint Classification: Pharmacodynamics Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Health Services Research
cytokines levels in patients with chronic low back pain and in healthy subjects
30 days after collect
No
Durval C Kraychet
Principal Investigator
Federal University of Bahia
Brazil: Ministry of Health
cytokine
NCT00991042
August 2003
March 2005
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