Inclusion Criteria:

1. Asymptomatic survivors treated with ≥ 25Gy to the abdomen, pelvis or spine, or ≥ 12Gy
total body radiation therapy, or ≥ 12Gy whole abdominal RT.

2. Patients who have passed ≥10 years following RT

3. Patients whose current age is 35-49.

Exclusion Criteria:

1. Patients with signs/symptoms suggestive of CRC or other high-risk features such as:

- Persistent constipation for >2 weeks in the last month

- One or more unexplained episodes of red blood in the stool in the last month

- One or more unexplained episodes of black stool in the last month

- Unexplained pelvic pain in the last month

2. Patients with a history of Crohn's disease or ulcerative colitis

3. Patients already taking part in a colorectal screening program defined as any
colorectal screening (colonoscopy, sigmoidoscopy, fecal occult blood test) within
last 5 years.

4. Patients with self-reported history of colorectal polyps.