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Image-Guided Stereotactic Biopsy of High Grade Gliomas


N/A
18 Years
89 Years
Open (Enrolling)
Both
Brain Cancer, Glioma

Thank you

Trial Information

Image-Guided Stereotactic Biopsy of High Grade Gliomas


Inclusion Criteria:



- Age > or = to 18 years old.

- Radiographic appearance of a lesion presumed to be high-grade glioma.

- Planned surgical resection.

Exclusion Criteria:

- All patients who have been previously treated with radiation, chemotherapy, or other
targeted drugs (patients only) for their brain tumor.

- Pregnant (confirmed by serum b-HCG in women of reproductive age) or breast feeding.

- Patients with other active malignancies or prior treatment for non-CNS malignancies.

Type of Study:

Interventional

Study Design:

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Outcome Measure:

invest relation btw voxel-based determ of prolif rate & obser MR imaging featu (i.e., Ktrans or microvas permeabil; fBV, tiss fract blood vol), as well with spatially reg histolog meas of tum cell prolif (Ki67) & microvas density (CD31) at corres locat.

Outcome Time Frame:

2 years

Safety Issue:

No

Principal Investigator

Michelle Bradbury, MD, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Memorial Sloan-Kettering Cancer Center

Authority:

United States: Food and Drug Administration

Study ID:

09-060

NCT ID:

NCT00979810

Start Date:

September 2009

Completion Date:

September 2013

Related Keywords:

  • Brain Cancer
  • Glioma
  • PET scan
  • CT scan
  • 09-060
  • CNS
  • Brain Neoplasms
  • Glioma

Name

Location
Memorial Sloan-Kettering Cancer Center New York, New York  10021