J-pouch Versus Side-to-end Coloanal Anastomosis After Preoperative Radiotherapy and Total Mesorectal Excision for Rectal Cancer: a Multicenter Randomized Trial
Invalidating anorectal dysfunctions are common after restorative rectal surgery. Improvement
of functional results by the technically more demanding J-pouch has been demonstrated in
comparison with the straight coloanal anastomosis. In the present multicenter randomized
trial we assessed whether the J-pouch is also superior to the side-to-end coloanal
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
Primary endpoint was the function of the neo-rectum as assessed by a validated functional outcome questionnaire at 4 months.
Netherlands: Medical Ethics Review Committee (METC)