A Clinical Trial of Increased Chest Radiotherapy Dose for Limited Stage Small Cell Lung Cancer
The ideal chest radiotherapy dose/fractionation scheme for limited stage small cell lung
cancer is undefined. Strategies of radiotherapy dose intensification with minimization of
overall treatment time are felt to improve cure rates for LS-SCLC. Hypofractionation (giving
higher than standard daily doses) facilitates both of these goals. In this study, we propose
to use a dose escalated hypofractionated regimen of chest radiotherapy for patients with
LS-SCLC.
Interventional
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
2-year overall survival
2011
No
Canada: Ethics Review Committee
24762
NCT00907569
June 2009
April 2011
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