CHP-901:Arterial Spin Labeling Perfusion MR Imaging in Pediatric Brain Tumors
N/A
18 Years
Both
Brain Tumors
Trial Information
CHP-901:Arterial Spin Labeling Perfusion MR Imaging in Pediatric Brain Tumors
The purpose of this study is to get information regarding the usefulness and accuracy of
this new MRI technique - termed arterial spin labeling (ASL) - in the diagnosis of pediatric
brain tumors. This technique can non-invasively measure the blood flow to the brain during
MRI examination. Because aggressive brain tumors require new blood vessels and a high level
of blood supply to support its growth, we believe the tumor blood flow measured using ASL is
a reliable indicator of tumor grade. This information may be useful for doctors to make
treatment decisions and to monitor patients' response to treatment.
Inclusion Criteria:
- Age 0-18 years
- Primary brain tumor (newly diagnosed or recurrent) with measurable disease (at least
1cm2)
Exclusion Criteria:
- Patients with cardiac pacemaker or ferrous metal foreign bodies
- Patients with medical problems contradictive to receiving MRI scans.
- Patients requiring general anesthesia or sedation for their MRI scan.
- Patients with a history of cerebrovascular disorders (stroke, moya moya) that may
alter cerebral perfusion.
Type of Study:
Observational
Study Design:
Observational Model: Case-Only, Time Perspective: Prospective
Principal Investigator
Michael Fisher, M.D.
Investigator Role:
Principal Investigator
Investigator Affiliation:
Children's Hospital of Philadelphia
Authority:
United States: Institutional Review Board
Study ID:
CHP 901 ASL
NCT ID:
NCT00907244
Start Date:
April 2008
Completion Date:
July 2012
Related Keywords:
- Brain Tumors
- Brain Neoplasms
Name | Location |
|---|---|
| The Children's Hospital of Philadelphia | Philadelphia, Pennsylvania 19104 |
