Michigan Center for Pancreatic Cancer Molecular Diagnosis: The Serum Protein Microarray Project
18 Years
N/A
Both
Pancreatic Cancer
Trial Information
Michigan Center for Pancreatic Cancer Molecular Diagnosis: The Serum Protein Microarray Project
OBJECTIVES:
- Identify specific proteins of interest to evaluate for their potential role as markers
for pancreatic cancer.
- Analyze serum proteins directly by mass spectrometry to identify new biomarkers of
pancreatic cancer that can be used for early diagnosis.
OUTLINE: Blood from patients is collected prior to treatment. Plasma proteins are analyzed
by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
(MALDI-TOF/MS) and/or electrospray mass spectrometry (ESI/MS).
PROJECTED ACCRUAL: A total of 120 patients will be accrued for this study.
Inclusion Criteria
DISEASE CHARACTERISTICS:
- Diagnosis of pancreatic cancer
- Newly diagnosed disease
- Planning to undergo surgery or other treatment for pancreatic cancer at Karmanos
Cancer Institute or its affiliates
PATIENT CHARACTERISTICS:
- Not specified
PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
Type of Study:
Observational
Study Design:
Observational Model: Case-Only, Time Perspective: Prospective
Outcome Measure:
Identification of specific proteins of interest to evaluate for their potential role as markers for pancreatic cancer
Outcome Time Frame:
Upon collection when patient agrees to provide a one time venous blood collection
Safety Issue:
No
Principal Investigator
Basil El-Rayes, MD
Investigator Role:
Study Chair
Investigator Affiliation:
Barbara Ann Karmanos Cancer Institute
Authority:
United States: Federal Government
Study ID:
CDR0000479140
NCT ID:
NCT00897494
Start Date:
February 2005
Completion Date:
April 2011
Related Keywords:
- Pancreatic Cancer
- stage I pancreatic cancer
- stage II pancreatic cancer
- stage III pancreatic cancer
- stage IV pancreatic cancer
- Pancreatic Neoplasms
Name | Location |
|---|---|
| Barbara Ann Karmanos Cancer Institute | Detroit, Michigan 48201 |
