Know Cancer

or
forgot password

Acquisition of Human Gynecologic Specimens to be Used in Studying the Causes, Diagnosis, Prevention and Treatment of Cancer


N/A
N/A
N/A
Open (Enrolling)
Female
Cancer

Thank you

Trial Information

Acquisition of Human Gynecologic Specimens to be Used in Studying the Causes, Diagnosis, Prevention and Treatment of Cancer


OBJECTIVES:

- Collect gynecological tumor specimens and blood from patients at GOG institutions.

- Provide a repository for long-term storage of these specimens.

OUTLINE: Snap frozen tumor tissue, OCT molds of tumor tissue, formalin-preserved tumor
tissue, buffy coat-prepared tumor tissue, and blood samples are collected and stored in the
repository. Patient information is kept confidential, and patients are not informed of any
research/test results from use of their tissues.

PROJECTED ACCRUAL: Not specified

Inclusion Criteria


DISEASE CHARACTERISTICS:

- Any of the following:

- Patients who have had gynecologic tissue removed during surgery to diagnosis,
treat, monitor, and/or prevent primary, persistent, or recurrent gynecologic
cancer of the ovary, peritoneum, fallopian tube, cervix, uterine corpus, vagina,
or vulva, meeting at least one of the following criteria:

- Group A: Women who underwent surgery, were diagnosed with a primary
gynecologic malignancy of the ovary, cervix, uterine corpus, or vulva, and
have primary tumor, normal tissue, and blood available for submission for
this protocol

- Patients with ovarian cancer including all stages, grades, and common
epithelial cell types

- Invasive cancers and serous and mucinous borderline tumors of low
malignant potential are allowed

- At least 1 gram of frozen primary tumor tissue must be submitted
for this protocol for patients with FIGO stage III or IV
epithelial ovarian cancer

- Patients with an invasive malignancy of the cervix or uterine corpus
including all stages, grades, and common cell types

- Patients with squamous cell carcinoma of the vulva

- Group B: Women who underwent surgery and were diagnosed with a rare
gynecologic malignancy of the ovary, peritoneum, fallopian tube, cervix,
uterine corpus, vagina, vulva, a gestational trophoblastic tumor, or a
tumor arising in endometriosis, and have tumor tissue available for
submission for this protocol

- Patients with a rare gynecologic malignancy of the ovary including
malignant germ cell tumors; sex cord-stromal tumors; malignant mixed
mesodermal tumors; clear cell, mucinous, small cell, or transitional
cell carcinomas; malignant Brenner tumors; or borderline tumors of low
malignant potential (except serous and mucinous)

- Patients with a rare gynecologic malignancy of the peritoneum,
including primary peritoneal cancer or mesothelioma

- Patients with carcinoma of the fallopian tube

- Patients with a rare gynecologic malignancy of the cervix including
verrucous, small cell, clear cell, serous, or adenoid cystic
carcinomas; carcinoid tumors; malignant mixed mesodermal tumors; or
leiomyosarcoma

- Patients with a rare gynecologic malignancy of the uterine corpus
including leiomyosarcoma; malignant mixed mesodermal tumors;
endometrial stromal sarcomas; smooth muscle tumors of unknown
malignant potential; or clear cell or small cell carcinomas

- Patients with a rare gynecologic malignancy of the vagina including
verrucous or clear cell carcinomas; melanoma; embryonal
rhabdomyosarcoma; or endodermal sinus tumor

- Patients with a rare gynecologic malignancy of the vulva including
verrucous carcinoma; melanoma; aggressive angiomyxoma; sarcoma;
malignant Paget's disease; or Bartholin gland carcinoma

- Patients with a gestational trophoblastic tumor

- Patients with a tumor arising in endometriosis

- Group C: Women who underwent prophylactic oophorectomy and have at least 1
gram of ovarian tissue and blood available for submission for this protocol

- Group D: Women who underwent surgery to monitor or treat a persistent or
recurrent gynecologic malignancy of the ovary, peritoneum, fallopian tube,
cervix, uterine corpus, vagina, or vulva, and have persistent or recurrent
tumor, normal tissue, and blood available for submission for this protocol

- Concurrent primary cancers are allowed

- No benign cystic tumors of the ovary, including cystic epithelial tumors and mature
cystic teratomas

PATIENT CHARACTERISTICS: Not specified

PRIOR CONCURRENT THERAPY:

Chemotherapy:

- Prior cytotoxic chemotherapy allowed

Endocrine therapy:

- Prior hormonal therapy allowed

Radiotherapy:

- Prior radiotherapy allowed

Surgery:

- Prior surgery allowed

- No more than 6 weeks after prior surgery

Type of Study:

Observational

Study Design:

N/A

Outcome Measure:

Collection of gynecological tumor specimens and serum from patients at GOG institutions

Safety Issue:

No

Principal Investigator

Michael L. Cibull, MD

Investigator Role:

Study Chair

Investigator Affiliation:

Lucille P. Markey Cancer Center at University of Kentucky

Authority:

Unspecified

Study ID:

CDR0000078647

NCT ID:

NCT00897442

Start Date:

June 1992

Completion Date:

Related Keywords:

  • Cancer
  • childhood malignant ovarian germ cell tumor
  • ovarian serous cystadenocarcinoma
  • ovarian serous cystadenoma with proliferating activity
  • recurrent ovarian germ cell tumor
  • recurrent ovarian epithelial cancer
  • stage IV ovarian epithelial cancer
  • stage III borderline ovarian surface epithelial-stromal tumor
  • stage IV borderline ovarian surface epithelial-stromal tumor
  • uterine corpus cancer
  • cervical adenocarcinoma
  • cervical adenosquamous cell carcinoma
  • cervical small cell carcinoma
  • cervical squamous cell carcinoma
  • recurrent cervical cancer
  • stage IA cervical cancer
  • stage IB cervical cancer
  • stage IIA cervical cancer
  • stage IIB cervical cancer
  • stage III cervical cancer
  • stage IVA cervical cancer
  • stage IVB cervical cancer
  • squamous cell carcinoma of the vulva
  • Brenner tumor
  • malignant mesothelioma
  • uterine leiomyosarcoma
  • endometrial stromal sarcoma
  • neoplasm of uncertain malignant potential
  • melanoma
  • embryonal childhood rhabdomyosarcoma
  • Paget disease of the vulva
  • gestational trophoblastic tumor
  • ovarian stromal cancer
  • ovarian clear cell cystadenocarcinoma
  • ovarian clear cell tumor with proliferating activity
  • stage IA ovarian germ cell tumor
  • stage IB ovarian germ cell tumor
  • stage IC ovarian germ cell tumor
  • stage IIA ovarian germ cell tumor
  • stage IIB ovarian germ cell tumor
  • stage IIC ovarian germ cell tumor
  • stage IIIA ovarian germ cell tumor
  • stage IIIB ovarian germ cell tumor
  • stage IIIC ovarian germ cell tumor
  • stage IA ovarian epithelial cancer
  • stage IB ovarian epithelial cancer
  • stage IC ovarian epithelial cancer
  • stage IIA ovarian epithelial cancer
  • stage IIB ovarian epithelial cancer
  • stage IIC ovarian epithelial cancer
  • stage IIIA ovarian epithelial cancer
  • stage IIIB ovarian epithelial cancer
  • stage IIIC ovarian epithelial cancer
  • recurrent primary peritoneal cavity cancer
  • stage IA primary peritoneal cavity cancer
  • stage IB primary peritoneal cavity cancer
  • stage IC primary peritoneal cavity cancer
  • stage IIA primary peritoneal cavity cancer
  • stage IIB primary peritoneal cavity cancer
  • stage IIC primary peritoneal cavity cancer
  • stage IIIA primary peritoneal cavity cancer
  • stage IIIB primary peritoneal cavity cancer
  • stage IIIC primary peritoneal cavity cancer
  • stage IV primary peritoneal cavity cancer
  • recurrent fallopian tube cancer
  • stage IA fallopian tube cancer
  • stage IB fallopian tube cancer
  • stage IC fallopian tube cancer
  • stage IIA fallopian tube cancer
  • stage IIB fallopian tube cancer
  • stage IIC fallopian tube cancer
  • stage IIIA fallopian tube cancer
  • stage IIIB fallopian tube cancer
  • stage IIIC fallopian tube cancer
  • stage IV fallopian tube cancer
  • recurrent endometrial carcinoma
  • stage I endometrial carcinoma
  • stage II endometrial carcinoma
  • stage III endometrial carcinoma
  • stage IV endometrial carcinoma
  • recurrent vaginal cancer
  • stage I vaginal cancer
  • stage II vaginal cancer
  • stage III vaginal cancer
  • stage IVA vaginal cancer
  • stage IVB vaginal cancer
  • recurrent vulvar cancer
  • stage I vulvar cancer
  • stage II vulvar cancer
  • stage III vulvar cancer
  • stage IVB vulvar cancer

Name

Location

National Naval Medical CenterBethesda, Maryland  20889
Fred Hutchinson Cancer Research CenterSeattle, Washington  98109
University of Michigan Comprehensive Cancer CenterAnn Arbor, Michigan  48109-0752
Barbara Ann Karmanos Cancer InstituteDetroit, Michigan  48201
CCOP - Iowa Oncology Research AssociationDes Moines, Iowa  50309-1016
George Bray Cancer Center at the Hospital of Central Connecticut - New Britain CampusNew Britain, Connecticut  06050
Baystate Regional Cancer Program at D'Amour Center for Cancer CareSpringfield, Massachusetts  01199
Case Comprehensive Cancer CenterCleveland, Ohio  44106-5065
Sanford Cancer Center at Sanford USD Medical CenterSioux Falls, South Dakota  57117-5039
Avera Cancer InstituteSioux Falls, South Dakota  57105
Vanderbilt-Ingram Cancer CenterNashville, Tennessee  37232-6838
University of Wisconsin Paul P. Carbone Comprehensive Cancer CenterMadison, Wisconsin  53792-6164
Marshfield Clinic - Marshfield CenterMarshfield, Wisconsin  54449
Medical College of Wisconsin Cancer CenterMilwaukee, Wisconsin  53226
Marshfield Clinic - Indianhead CenterRice Lake, Wisconsin  54868
CCOP - Cancer Research for the OzarksSpringfield, Missouri  65807
CCOP - GreenvilleGreenville, South Carolina  29615
University of Texas Medical BranchGalveston, Texas  77555-1329
Virginia Mason Medical CenterSeattle, Washington  98111
Holden Comprehensive Cancer Center at University of IowaIowa City, Iowa  52242-1002
UMASS Memorial Cancer Center - University CampusWorcester, Massachusetts  01605-2982
Ellis Fischel Cancer Center at University of Missouri - ColumbiaColumbia, Missouri  65203
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical CenterLebanon, New Hampshire  03756-0002
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel HillChapel Hill, North Carolina  27599-7570
Charles M. Barrett Cancer Center at University HospitalCincinnati, Ohio  45267-0526
UPMC Cancer Center at Magee-Womens HospitalPittsburgh, Pennsylvania  15213-3180
MultiCare Regional Cancer Center at Tacoma General HospitalTacoma, Washington  98405
Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsBaltimore, Maryland  21231-2410
Cleveland Clinic Taussig Cancer CenterCleveland, Ohio  44195
Brooke Army Medical CenterFort Sam Houston, Texas  78234-6200
CCOP - Virginia Mason Research CenterSeattle, Washington  98101
Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical CenterMilwaukee, Wisconsin  53201-2901
University of California Davis Cancer CenterSacramento, California  95817
Fletcher Allen Health Care - University Health Center CampusBurlington, Vermont  05401
John Stoddard Cancer Center at Iowa Methodist Medical CenterDes Moines, Iowa  50309
Sunrise Hospital and Medical CenterLas Vegas, Nevada  89109-2306
Arkansas Cancer Research Center at University of Arkansas for Medical SciencesLittle Rock, Arkansas  72205
Swedish Cancer Institute at Swedish Medical Center - First Hill CampusSeattle, Washington  98104
Northside Hospital Cancer CenterAtlanta, Georgia  30342-1611
St. John's Regional Health CenterSpringfield, Missouri  65804
Winthrop University HospitalMineola, New York  11501
McDowell Cancer Center at Akron General Medical CenterAkron, Ohio  44307
Lake/University Ireland Cancer CenterMentor, Ohio  44060
Women and Infants Hospital of Rhode IslandProvidence, Rhode Island  02905
Carilion Gynecologic Oncology AssociatesRoanoke, Virginia  24014
Wilford Hall Medical CenterLackland Air Force Base, Texas  78236-5300
Yale Cancer CenterNew Haven, Connecticut  06520-8028
Advocate Christ Medical CenterOak Lawn, Illinois  60453
Mount Sinai Medical CenterNew York, New York  10029
Stony Brook University Cancer CenterStony Brook, New York  11794-8174
Wake Forest University Comprehensive Cancer CenterWinston-Salem, North Carolina  27157-1096
Hollings Cancer Center at Medical University of South CarolinaCharleston, South Carolina  29425
Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - DallasDallas, Texas  75390
Sibley Memorial HospitalWashington, District of Columbia  20016
St. Elizabeth Medical CenterEdgewood, Kentucky  41017
Riverside Methodist Hospital Cancer CareColumbus, Ohio  43214
University Cancer Center at University of Washington Medical CenterSeattle, Washington  98195
Jonsson Comprehensive Cancer Center at UCLALos Angeles, California  90095-1781
UCSF Helen Diller Family Comprehensive Cancer CenterSan Francisco, California  94115
Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical CenterSavannah, Georgia  31403-3089
University of Illinois Cancer CenterChicago, Illinois  60612-7243
Indiana University Melvin and Bren Simon Cancer CenterIndianapolis, Indiana  46202-5289
Lucille P. Markey Cancer Center at University of KentuckyLexington, Kentucky  40536-0093
University of Mississippi Cancer ClinicJackson, Mississippi  39216-4505
Siteman Cancer Center at Barnes-Jewish Hospital - Saint LouisSt. Louis, Missouri  63110
University of New Mexico Cancer CenterAlbuquerque, New Mexico  87131-5636
Oklahoma University Cancer InstituteOklahoma City, Oklahoma  73104
Methodist Estabrook Cancer CenterOmaha, Nebraska  68114-4199
Robert H. Lurie Comprehensive Cancer Center at Northwestern UniversityChicago, Illinois  60611
Todd Cancer Institute at Long Beach Memorial Medical CenterLong Beach, California  90801
Maine Medical Center - Bramhall CampusPortland, Maine  04102
Cleveland Clinic Cancer Center at Fairview HospitalCleveland, Ohio  44111
Hillcrest Cancer Center at Hillcrest HospitalMayfield Heights, Ohio  44124
Cancer Care Associates - Saint Francis CampusTulsa, Oklahoma  74136-1929
Rosenfeld Cancer Center at Abington Memorial HospitalAbington, Pennsylvania  19001
Morgan Cancer Center at Lehigh Valley Hospital - Cedar CrestAllentown, Pennsylvania  18105
Fox Chase Cancer Center - PhiladelphiaPhiladelphia, Pennsylvania  19111-2497
Parkland Memorial HospitalDallas, Texas  75235
John Stoddard Cancer Center at Iowa Lutheran HospitalDes Moines, Iowa  50316-2301
Medical Oncology and Hematology Associates at John Stoddard Cancer CenterDes Moines, Iowa  50309
Medical Oncology and Hematology Associates at Mercy Cancer CenterDes Moines, Iowa  50314
Mercy Cancer Center at Mercy Medical Center - Des MoinesDes Moines, Iowa  50314
Medical Oncology and Hematology Associates - West Des MoinesWest Des Moines, Iowa  50266
Western Pennsylvania Cancer Institute at Western Pennsylvania HospitalPittsburgh, Pennsylvania  15224-1791
Praxair Cancer Center at Danbury HospitalDanbury, Connecticut  06810
Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer CenterColumbus, Ohio  43210-1240
Legacy Good Samaritan Hospital & Comprehensive Cancer CenterPortland, Oregon  97210
Northwest Cancer Specialists at Rose Quarter Cancer CenterPortland, Oregon  97227
Marshfield Clinic - Chippewa CenterChippewa Falls, Wisconsin  54729
Marshfield Clinic Cancer Care at Regional Cancer CenterEau Claire, Wisconsin  54701
Saint Joseph's HospitalMarshfield, Wisconsin  54449
Marshfield Clinic - Lakeland CenterMinocqua, Wisconsin  54548
Marshfield Clinic at Saint Michael's HospitalStevens Point, Wisconsin  54481
Saint Michael's Hospital Cancer CenterStevens Point, Wisconsin  54481
Marshfield Clinic - Wausau CenterWausau, Wisconsin  54401
Marshfield Clinic - Weston CenterWeston, Wisconsin  54476
Diagnostic and Treatment CenterWeston, Wisconsin  54476
Marshfield Clinic - Wisconsin Rapids CenterWisconsin Rapids, Wisconsin  54494
Woman's HospitalBaton Rouge, Louisiana  70815
FirstHealth Moore Regional Community Hospital Comprehensive Cancer CenterPinehurst, North Carolina  28374
Fox Chase Cancer Center CCOP Research BasePhiladelphia, Pennsylvania  19140
Seattle Cancer Care AllianceSeattle, Washington  98109
Regional Cancer Center at Memorial Medical CenterSpringfield, Illinois  62781-0001
Methodist HospitalHouston, Texas  77030
Aurora Sinai Medical CenterMilwaukee, Wisconsin  53201-0342
Seton Shivers Cancer Program at Brackenridge HospitalAustin, Texas  78701
Cancer Centers of the Carolinas - Faris RoadGreenville, South Carolina  29605
Cancer Centers of the Carolinas - SpartanburgSpartanburg, South Carolina  29307
Pacific Gynecology SpecialistsSeattle, Washington  98104
MBCCOP - Meharry Medical College - NashvilleNashville, Tennessee  37208-3599
Louisville Oncology at Norton Cancer Institute - LouisvilleLouisville, Kentucky  40202
Women's Cancer Center - La CanadaLas Vegas, Nevada  89169
Good Samaritan Hospital Cancer Treatment CenterCincinnati, Ohio  45220
Olive View - UCLA Medical Center FoundationSylmar, California  91342
University of Colorado Cancer Center at UC Health Sciences CenterAurora, Colorado  80045
Christus Schumpert Cancer Treatment CenterShreveport, Louisiana  71101
Florida Gynecologic Oncology - Fort MyersFort Myers, Florida  33905
St. Dominic Cancer CenterJackson, Mississippi  39216
Black Hills Obstetrics & Gynecology LLPRapid City, South Dakota  57701
Chattanooga's Program in Women's OncologyChattanooga, Tennessee  37403
Aurora Women's Pavilion of West Allis Memorial HospitalWest Allis, Wisconsin  53227
Roy and Patricia Disney Family Cancer Center at Providence Saint Joseph Medical CenterBurbank, California  91505
Marshfield Clinic - Ladysmith CenterLadysmith, Wisconsin  54848
Mercy Cancer Center - West LakesClive, Iowa  50325
Methodist West HospitalWest Des Moines, Iowa  50266-7700