Inclusion Criteria:

- Patients with large operable lesions (pT/cT > 5 cm) or locally advanced breast
cancers undergoing modified radical mastectomy or breast conservative surgery-(BCS)
who need adjuvant post operative radiotherapy

- Patients post mastectomy requiring radiotherapy because of nodal positivity

- Completed planned chemotherapy schedule

- ER and/or PR positive patients

- Patients decided to be put on tamoxifen

- Patients reliable for follow up

Exclusion Criteria:

- Patients with BCT who have pT1 or pT2 breast lesions (N0,N1)

- Patients for palliative radiotherapy to the chest wall/breast/supraclavicular fossa

- Any patient requiring radiation to the axillary or internal mammary area

- Recurrent disease or metastatic disease

- Patients on concurrent chemotherapy and radiation