Inclusion Criteria:

- Women with newly diagnosed histologically confirmed FIGO Stage IB-IVA carcinoma of
the cervix, including squamous, adenosquamous or adenocarcinoma. Women not suitable
for surgery due to comorbidities (medical or other conditions) are also considered
eligible.

- Age equal to or greater than 18 years

- Being considered for treatment with curative intent using concurrent chemotherapy and
pelvic RT.

Exclusion Criteria:

- ECOG performance status greater than 2.

- Other cervical cancer tumour types (e.g. neuroendocrine, serous).

- Carcinoma of the cervical stump.

- Prior hysterectomy.

- Patients who, at the time of the initial evaluation, have already undergone a whole
body PET-CT within the last 6 months.

- Contraindications to 18FDG PET-CT or CT of the abdomen and pelvis.

- Inability to lie supine for imaging with PET-CT.

- Contraindication to radiotherapy (i.e., significant Crohn's disease).

- Contraindication to cisplatin chemotherapy (i.e., non-reversible renal failure).

- Inadequate bone marrow function: ANC less than 1.5 X 10^9, platelets less than 100 X
10^9.

- Inadequate renal function: Creatinine greater/equal to 150 micromol/L

- Inadequate hepatic function: Bilirubin greater than 1.5 X ULN and SGOT and Alkaline
Phosphatase greater than 3 X ULN.

- History of another invasive malignancy within the previous 5 years with the exception
of non-melanoma skin cancer.

- Other medical conditions that may preclude chemo-radiation therapy.

- Known pregnancy or lactating.

- Inability to complete study or required follow-up.