The Impact of Positron Emission Tomography (PET) Imaging in Women With Locally Advanced Cervical Cancer
Cervical cancer is the second most common cause of cancer deaths worldwide. In Canada, it is
estimated that in 2009 there will be 1,300 new cases of cervical cancer and that 380 women
will die of this disease. The corresponding 2009 data for Ontario is 500 new cases and 140
deaths. In Canada, cervical cancer screening with the Pap test allows for the diagnosis and
curative treatment of precancerous lesions of the cervix or early cervical cancers. Symptoms
of cervical cancer include vaginal bleeding and discharge. Unfortunately these are often
associated with more advanced disease.
The costs associated with health care are increasing. PET is an expensive imaging modality.
Given that resources for health care are not unlimited, there needs to be high quality
evidence of an intervention such as PET's efficacy.
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Treatment delivered between patients having whole body 18FDG PET-CT in addition to CT of the abdomen and pelvis versus patients having a CT of the abdomen and pelvis alone.
Laurie Elit, MD
Juravinski Cancer Centre, Canada
Canada: Health Canada