Inclusion Criteria:

- Written informed consent must be obtained.

- Patient must be 18 years or older.

- Are male or non-pregnant, non-lactating females.

- Patients enrolled in Phase I must be candidates for surgical liver resection per a
treating surgeon's discretion. Patients enrolled in Phase 2-3 must be candidates for
surgical liver resection of liver mass. Patients enrolled in Phase 4 must be
candidates for surgical ablation, but not candidates for surgical resection

Exclusion Criteria:

- Any condition which, in the judgment of the investigator, might increase the risk to
the subject or decrease the chance of obtaining satisfactory data to achieve the
objectives of the study.

- Mental condition rendering the subject or his/her legal representative unable to
understand informed consent to the nature, scope, and possible consequences of the
study.