Inclusion Criteria:

- The women had to be 18 to 75 years of age with a nonmetastatic breast adenocarcinoma
treated by either lumpectomy or mastectomy with or without adjuvant postoperative
chemotherapy or hormonal treatment, and referred to the Department of Radiotherapy
for postoperative radiotherapy. Concomitant chemotherapy was allowed.

Exclusion Criteria:

- Women with bilateral cancer, patients who were allergic to either of the two agents,
and pregnant women were excluded.

- No rash, ulceration, bleeding, or unhealed scar was allowed in the treatment area.

- Patients were excluded for: prior radiation therapy (RT), mastectomy, skin
involvement by tumor, history of, or current connective tissue disorder, medical
contraindication (allergy or sensitivity) to Aloevera or planned BSC, and inability
to comply with treatment regime. The use of bolus was prohibited.