Improving the Therapeutic Ratio by Using Proton Beam Radiation Therapy for Patients With Stage IA-IIIBX (Bulky/Non-bulky) Hodgkin Lymphoma Involving the Mediastinum Following Standard Chemotherapy
3 treatment plans will be created to deliver between a total of 21-45.6 Gy/CGE to the
planning target volume.
1. Proton Plan
2. Conventional Plan
3. IMRT Plan
The patient will then receive the radiation modality with the lowest body V4Gy/CGE
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
To assess the reduction of normal tissue exposed to greater than or equal to 4 Gy/CGE with use of proton therapy compared to photon therapy.
Prior to starting radiation therapy
Bradford S Hoppe, MD, MPH
University of Florida Proton Therapy Institute
United States: Institutional Review Board
UFPTI 0806 - HL01
|University of Florida Proton Therapy Institute||Jacksonville, Florida 32206|