Measurement of the Folate Receptor in Blood
18 Years
N/A
Both
Healthy
Trial Information
Measurement of the Folate Receptor in Blood
A method has been developed in the laboratory which has been able to measure FR obtained
from cancer cells in culture that has been added into blood. We would like to study if this
method can measure FR in plasma and serum obtained from patients with ovarian cancer. We
would also like to analyse plasma and serum samples obtained from healthy volunteers to
determine if they have any appreciable levels of FR, which can then be compared to the
measurements obtained from cancer patients.
Inclusion Criteria:
- Patients with stage III/IV ovarian cancer
- healthy volunteers who are staff at the ICR and RMH
Exclusion Criteria:
- patients or healthy volunteers who are unable to give informed consent
- pregnancy
Type of Study:
Observational
Study Design:
N/A
Outcome Measure:
To measure the levels of folate receptor in blood samples obtained from patients with ovarian cancer and from healthy volunteers
Safety Issue:
No
Principal Investigator
Stan Kaye, Professor
Investigator Role:
Principal Investigator
Investigator Affiliation:
Royal Marsden NHS Foundation Trust
Authority:
United Kingdom: Research Ethics Committee
Study ID:
CCR3028
NCT ID:
NCT00838747
Start Date:
September 2008
Completion Date:
July 2011
Related Keywords:
- Healthy
- folate receptor
- blood samples
- ovarian cancer
- development of measure of folate receptor in blood samples
- possible selection of patients for treatment with FR targeted agents
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