Phase ⅡStudy of Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation for Stage ⅣAB Nasopharyngeal Carcinoma
Concurrent chemoradiation is the standard treatment for locally advanced NPC. The survival
benefit gained from adding neoadjuvant chemotherapy to concurrent chemoradiation has never
been defined. In the present trail, we hope to assess the tolerance and survival benefits
of neoadjuvant chemotherapy followed by concurrent chemoradiation in patients with stage ⅣAB
NPC.
Interventional
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
overall survival
3 and 5 years
Yes
Lin Kong, MD
Principal Investigator
Department of Radiation Oncology, Cancer Hospital, Fudan University
China: Ethics Committee
NPC-0703
NCT00816816
February 2007
June 2010
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