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A Prospective Evaluation of the Informational Content of Setup Verification Images for Patients Receiving Breast Radiation Therapy Tangentially With or Without Supraclavicular Treatment


N/A
N/A
N/A
Not Enrolling
Both
Breast Cancer

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Trial Information

A Prospective Evaluation of the Informational Content of Setup Verification Images for Patients Receiving Breast Radiation Therapy Tangentially With or Without Supraclavicular Treatment


Accurate patient positioning is critical in Radiation Therapy. Electronic imaging is used
to compare a patient's actual treatment position, with that which was planned from an
initial CT scan. Radiation Therapists compare planned and actual images using analysis
software to determine if differences are within acceptable tolerances. At the VIC, we use 3
different breast imaging protocols depending on the patient set-up and treatment technique.
Findings from our recent retrospective planning study show that our current electronic
imaging protocols miss some clinically significant patient set-up errors, particularly in
the medial/lateral direction, and that these errors can be better detected with the use of
an anterior image. The purpose of this study is to test these findings prospectively in
clinical practice, through the direct comparison of our current protocols with a proposed
new protocol, which would include an anterior electronic portal image (EPI).


Inclusion Criteria:



- All patients (male or female) receiving tangential breast/chest wall radiotherapy
only, or three or four field breast/chest wall and nodal radiotherapy will be
eligible.

Exclusion Criteria:

- Those patients receiving partial breast treatment, those patients requiring an
electron match field, those on another breast cancer radiotherapy trial, those who
require radiotherapy using deep inspiration breath hold or multi-field intensity
modulated radiotherapy, and all non-breast cancer patients will be excluded.

Type of Study:

Interventional

Study Design:

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Outcome Measure:

To measure the difference in accuracy of a breast imaging protocol that includes a large anterior EPI in detecting set-up errors outside of tolerance as compared to the current standard breast imaging protocols.

Outcome Time Frame:

Will be measured on days 1, 2 and 3 of radiation therapy and possibly day 4 if adjustments of the EPI where required.

Safety Issue:

Yes

Principal Investigator

Elaine Wai

Investigator Role:

Principal Investigator

Investigator Affiliation:

British Columbia Cancer Agency

Authority:

Canada: Ethics Review Committee

Study ID:

BCCA002

NCT ID:

NCT00800189

Start Date:

August 2008

Completion Date:

August 2011

Related Keywords:

  • Breast Cancer
  • Breast Neoplasms

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