Know Cancer

forgot password

microRNA Expression in Renal Cell Carcinoma

18 Years
Open (Enrolling)
Carcinoma, Renal Cell

Thank you

Trial Information

microRNA Expression in Renal Cell Carcinoma

Due to the lack of specific indicators for the early diagnosis of RCC, the RCC patients
often have distant metastasis when diagnosed and their five-year survival rate is much low.
Therefore, the biological markers of RCC are needed for early detection, early treatment and
improvement of the survival rate of RCC patients.

MiRNA and tumor are closely related. MiRNA can control the important cancer-related genes
and participate in the tumor cell proliferation, apoptosis, invasion and angiogenesis.

In this study, renal cell carcinoma(RCC) related miRNA and the target genes of related miRNA
will be examined,and the relationship between RCC related miRNA and the RCC pathological
types, TNM (tumor-nodes-metastasis) stages and prognosis will be analyzed. The purpose of
this study is to investigate the role of miRNA in the formation of RCC and look for the
biomarker of RCC.

Inclusion Criteria:

- Patients with primary renal cell carcinoma.

- Subjects who agree to participate in the study and sign the informed consent.

Exclusion Criteria:

- Patients with secondary renal cell carcinoma.

- Subjects who refuse to participate in the study and sign the informed consent.

Type of Study:


Study Design:

Observational Model: Case-Only, Time Perspective: Cross-Sectional

Principal Investigator

Xueqing Yu, M.D. & Ph.D.

Investigator Role:

Principal Investigator

Investigator Affiliation:

1st Affiliated Hospital, Sun Yat-Sen University


China: Food and Drug Administration

Study ID:




Start Date:

July 2008

Completion Date:

August 2011

Related Keywords:

  • Carcinoma, Renal Cell
  • Carcinoma, Renal Cell
  • MicroRNAs
  • Carcinoma
  • Carcinoma, Renal Cell