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Long-term Evaluation of the Quality of Life After Major Hepatic Resection for Malignant and Benign Diseases.


N/A
18 Years
N/A
Open (Enrolling)
Both
Liver Diseases, Liver Neoplasms

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Trial Information

Long-term Evaluation of the Quality of Life After Major Hepatic Resection for Malignant and Benign Diseases.


Background: Due to advances in operative methods and perioperative care, mortality and
morbidity following major hepatic resection have decreased substantially, making long-term
quality of life (QoL) an increasingly prominent issue.

Objectives: We plan on evaluating whether postoperative diagnosis is associated with
long-term QoL and health in patients who require hepatic surgery for benign or malignant
diseases and how QoL evolves with time.

Method: QoL will be evaluated using the European Organization for Research and Treatment of
Cancer Quality of Life Questionnaire Core-30 and the liver-specific QLQ-LMC21 module. All
patients requiring hepatic surgery aged >18 years will be included in the study. QoL
evaluation is carried out preoperatively and at set intervals postoperatively.


Inclusion Criteria:



- Patients with planned liver resection

Exclusion Criteria

- Patients with biopsy of the liver only

- Inability of understanding the questionnaire

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

Quality of Life

Outcome Time Frame:

preoperatively, 1-,3-,6-,12 months postoperatively

Safety Issue:

No

Principal Investigator

Vanessa Banz, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Dep. of Visceral and transplant Surgery, University Hospital Berne, Switzerland

Authority:

Switzerland: Ethikkommission

Study ID:

KEK 18/08

NCT ID:

NCT00681499

Start Date:

February 2008

Completion Date:

January 2014

Related Keywords:

  • Liver Diseases
  • Liver Neoplasms
  • Quality of Life
  • Liver Neoplasms
  • Surgical procedures, Operative
  • Neoplasms
  • Liver Diseases
  • Liver Neoplasms

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