Comparing the Test Characteristics of Three Oral Cancer Screening Techniques:1)Unaided Visual Examination 2)VelScope Examination and 3)Toluidine Blue Application, by Trained Primary Health Care Workers in Mumbai, India.
Oral cancer is the most common cancer among men in India mainly due to the habit of using
smokeless tobacco. Pre-cancerous lesions like leukoplakia, melanoplakia, erythroplakia,oral
submucous fibrosis and indolent ulcers can be easily detected by periodic examination of the
oral cavity of the at-risk populations. Several methods of oral cancer screening have been
tried over the past three-four decades with varying success. This study investigates the
feasibility of application and compares the test characteristics of three oral cancer
screening techniques: Unaided Visual Inspection, VelScope assisted examination and
examination after application of Toluidine blue dye by primary health care workers among
tobacco users attending a cancer early detection clinic, in Mumbai, India.
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Screening
To evaluate the feasibility and efficacy of performance of the three oral cancer screening tests viz. naked eye unaided examination , examination using VELScope and after application of Toluidine Blue by trained primary health workers.
Surendra S Shastri, MD
Tata Memorial Hospital
India: Indian Council of Medical Research