A Pilot Study of PET-CT in the Assessment of Pulmonary Nodules in Children With Malignant Solid Tumors
In this study, we seek to assess the feasibility of performing PET-CT for the evaluation of
pulmonary nodules in children to obtain preliminary data for sample size determination for a
larger multi-institutional trial. The primary objective of the multi-institutional trial
will be to compare the accuracy of diagnostic CT alone to PET-CT in distinguishing benign
from malignant nodules in children with solid malignancies. We are hopeful that PET-CT will
allow us to better direct the clinical management of these patients and to reduce the number
of invasive procedures performed to confirm the presence of benign disease.
Observational Model: Cohort, Time Perspective: Cross-Sectional
To assess the feasibility of performing PET-CT for the evaluation of pulmonary nodules in children with solid malignancies and to obtain preliminary data for sample size determination for a larger, multi-institutional prospective study.
Mary E McCarville, MD
St. Jude Children's Research Hospital
United States: Institutional Review Board
|Mary E. McCarville||Memphis, Tennessee 38105|