Novel Rinse to Treat Oral Candidiasis in Cancer Patients "Evaluate Iocide Oral Rinse in Any Patient With Thrush, Including But Not Limited to Patients Currently Receiving or Post Radiation Therapy for Head and Neck Cancer or Patients Positive for HIV/AIDS or Transplant Patients"
A four-week study has been designed as an assessment of the clinical cure and mycological
eradication of oral Candida isolates in 40 cancer patients referred by radiation oncologists
during the course of his/her treatment. An estimated 35 patients will be evaluable at the
end of the study. Candida infection is defined as positive clinical signs (white plaques)
with positive potassium hydroxide (KOH) preparation and positive cultures. Colonization is
defined as a positive culture without signs of clinical infection.
Observational Model: Case-Only, Time Perspective: Prospective
The primary analysis will be "intention to treat."
Spencer W. Redding, DDS
University of Texas Health Science Center at San Antonio
United States: Food and Drug Administration
|University of Missouri at Kansas City, School of Dentistry||Kansas City, Missouri 64108|
|Cancer Therapy and Researh Center||San Antonio, Texas 78229|