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Imaging of Prostate Cancer Using Two-Dimensional MR Spectroscopy and Diffusion Tensor Imaging

21 Years
80 Years
Not Enrolling
Prostate Lesions

Thank you

Trial Information

Imaging of Prostate Cancer Using Two-Dimensional MR Spectroscopy and Diffusion Tensor Imaging

Inclusion Criteria:

1. A male older than 21 years of age and under age of 80,

2. Either a normal healthy volunteer; a patient who has confirmed prostate cancer and
decided to receive prostatectomy; or a patient who has persistent elevated PSA higher
than 4.0 ng/ml, and with a prior benign biopsy scheduled to receive the second

Exclusion Criteria:

1. Unwilling to give informed consent,

2. Have implanted prosthetic heart valves, pacemaker, neuro-stimulation devices,
surgical clips (hemostatic clips) or other metallic implants,

3. Have engaged in occupations or activities which may cause accidental lodging of
ferromagnetic materials, or have imbedded metal fragments from military activities,

4. Have received orthodontic work involving ferromagnetic materials,

5. Claustrophobic,

6. Unable to lie down still for 60 minutes.

Type of Study:


Study Design:

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Outcome Measure:

To demonstrate that multi-voxel MR spectroscopy and diffusion tensor imaging can accurately diagnose prostate cancer and benign diseases, also to provide an accurate disease extent.

Outcome Time Frame:

at completion of the study

Safety Issue:


Principal Investigator

Min-Ying Su, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

University of California, Irvine


United States: Institutional Review Board

Study ID:




Start Date:

June 2007

Completion Date:

Related Keywords:

  • Prostate Lesions
  • Prostatic Neoplasms



Center for Functional Onco-Imaging, University of California Irvine, California  92697