Comparison of Computer-Driven Protocolized Weaning With Physician-Directed Weaning in Surgical Intensive Care Unit (ICU) Patients
Since long-term mechanical ventilation is affiliated with a bunch of complications, weaning
affected patients from ventilation as soon as possible is a crucial point. In this context
automated computerized systems have become a torchbearer. These systems are expected to
expedite the weaning process, reduce the duration of mechanical ventilation and ICU length
of stay of a given patient in comparison to conventional physician-directed weaning. A
multicenter randomized trial by Lellouche et al supported these theories, using a
computer-driven system to regulate Pressure Support Ventilation (PSV). This system is now
commercially available as SmartCare/PS (Draeger Medical AG & Co. KG, Luebeck, Germany).
The purpose of the study on hand was to find out whether the results reported before could
be repeated in a broad, surgical ICU patient group. Study design was chosen similar. In
addition we investigated the workload for physicians and nurses in both study arms which has
not been conducted before.
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
measured in days
Elke Muhl, Prof. Dr. med.
University of Luebeck
Germany: Federal Institute for Drugs and Medical Devices