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Breast MRI as a Preoperative Tool for DCIS

21 Years
59 Years
Open (Enrolling)
Breast Cancer, Ductal Carcinoma in Situ

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Trial Information

Breast MRI as a Preoperative Tool for DCIS

Inclusion Criteria:

- Age less than 60 at time of consent

- Clinical stage is consistent with Stage 0 or Stage I T1mic at presentation

- Core biopsy proven DCIS or DCIS with microinvasion (invasion ≤0.1 cm), prior to

- Breast surgery to be performed at MSKCC

- Informed consent obtained

- Female

Exclusion Criteria:

- Age 60 or over at time of consent

- Patients who are pregnant or nursing

- Patients with contraindications to breast conservation

- Excisional biopsy of DCIS or DCIS with microinvasion, prior to enrollment

- Patients with any contraindications to MRI including pacemaker, tissue expander,
other metallic surgical implants, weight over 350 lb., previous gadolinium reaction,
metal fragments in eye

Type of Study:


Study Design:

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Outcome Measure:

To prospectively evaluate the value of preoperative breast MRI in women with core biopsy-proven DCIS.

Outcome Time Frame:

conclusion of the study

Safety Issue:


Principal Investigator

Kimberly Van Zee, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Memorial Sloan-Kettering Cancer Center


United States: Institutional Review Board

Study ID:




Start Date:

October 2006

Completion Date:

October 2013

Related Keywords:

  • Breast Cancer
  • Ductal Carcinoma In Situ
  • MRI
  • Breast Neoplasms
  • Carcinoma
  • Carcinoma in Situ
  • Carcinoma, Intraductal, Noninfiltrating
  • Carcinoma, Ductal, Breast
  • Carcinoma, Ductal



Memorial Sloan Kettering Cancer Center New York, New York  10021
Memorial Sloan-Kettering Cancer Center New York, New York  10021
Memoral Sloan Kettering Cancer Center Basking Ridge, New Jersey