Inclusion Criteria:

- Must have biopsy proven mantle cell lymphoma confirming mantle cell lymphoma. (Flow
cytometry, and cyclin D1 or t (11;14) tests of disease site should be done if
available at some time in the patient's course before this therapy)

- Radiologic staging studies may be performed up to 6 weeks prior to starting therapy
and not be repeated if the treating physician feels it unnecessary

- No other prior malignancy is permitted except for adequately treated basal cell or
squamous cell skin cancer, in situ cervical cancer, or other cancer for which the
patient has been disease-free for one year.

- Age > or = to 18 years of age

- For patients who are in first remission from a prior regimen, at least 3 weeks must
elapse from a prior chemotherapy and at least 1 week from radiation or antibody
therapy.

Exclusion Criteria:

- Significant medical and/or psychiatric illness which, in the opinion of the
investigators, may compromise any aspect of the planned treatment.

- The patient cannot have been exposed to chemotherapy to treat any of these diseases
(other than mantle cell lymphoma) for at least 3 years prior to entry on this
protocol.