Molecular Imaging of Breast Cancer With Breast PET/CT
18 Years
N/A
Female
Breast Cancer
Trial Information
Molecular Imaging of Breast Cancer With Breast PET/CT
PET is literally a molecular imaging modality. In monitoring the patient's response to a
specific chemotherapeutic regime, baseline and subsequent PET/CT scans can be used to
quantitatively determine the therapeutic effect of the regime, using the standard uptake
value (SUV), a common metric in PET imaging. The breast PET/CT system will facilitate
molecular imaging of breast cancer using a number of radiolabeled molecules, available both
commercially (18-FDG) and from the research environment.
Inclusion Criteria:
- Normal Adult Volunteers
- Female, at least 18 years of age
- Ability to lie motionless for up to 20 minutes
Patient Volunteers
- Female, at least 18 years of age
- Diagnostic findings from prior mammography highly suggestive of invasive breast
carcinoma (BI-RADS category 5)
- Not pregnant or breast-feeding
- Ability to lie motionless for up to 20 minutes
Exclusion Criteria:
- Normal Adult Volunteers
- Inability to understand the risks and benefits of the study
Patient Volunteers
- Recent breast biopsy
- Diagnostic findings from prior mammography highly suggestive of noninvasive ductal or
lobular carcinoma
- Uncontrolled diabetes
- Diabetic and blood sugar level > 200 mg/dL
- Positive urine pregnancy test or currently breast-feeding
- Inability to understand the risks and benefits of the study
Type of Study:
Interventional
Study Design:
Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Outcome Measure:
End-points of this study are whether women will accept the imaging position and timing, and whether functional properties of breast cancer can be imaged with this device.
Outcome Time Frame:
5 years
Safety Issue:
Yes
Principal Investigator
Ramsey Badawi, PhD
Investigator Role:
Principal Investigator
Investigator Affiliation:
University of California, Davis
Authority:
United States: Institutional Review Board
Study ID:
200715040
NCT ID:
NCT00584753
Start Date:
April 2007
Completion Date:
July 2011
Related Keywords:
- Breast Cancer
- Breast cancer
- Breast Neoplasms
Name | Location |
|---|---|
| UC David Medical Center | Sacramento, California 95817 |
