Inclusion Criteria:

- Registered and being treated on one of the following therapeutic protocols:

06-043, 07-052, 07-057, 07-112, 07-116, 08-093, and 08-054

- Have at least one measurable lesion* as per RECIST criteria situated in lung, liver
or lymph node meeting RECIST criteria noted on a baseline CT scan.

- Baseline** and at least one follow-up CT scan to likely to be obtained at an MSKCC
facility

- All patients must be > or = to 18 years old

- The measurable lesions are metastatic in the liver, lung and lymph nodes. The
algorithms do not distinguish between primary and metastatic disease, therefore,
in selected cases, a primary lesion such as in the liver or lung may also be
assessed.

- Baseline CT are prefer but if not able to obtain for volumetric
reconstructions follow up studies will still be use for other objectives if
the study.

Exclusion Criteria:

- Pregnant or lactating women