Inclusion Criteria:

- Provide written informed consent.

- 21 years of age or older.

- Histologically confirmed diagnosis of colorectal carcinoma (patients only).

- Resected primary colorectal cancer and no metastatic disease or primary colorectal
cancer with no metastatic disease and planned resection after neo-adjuvant
chemotherapy or metastatic colorectal carcinoma considered by the attending physician
to have resectable or potentially resectable hepatic metastases (patients only). Each
patient will be staged by his/her attending physician in the Department of Medicine
or Surgery. Hepatic metastases are considered resectable if they are expected to be
completely removable with negative margins by a procedure that leaves behind
sufficient liver parenchyma with arterial/portal blood supply, venous drainage and
biliary drainage for subsequent regeneration and survival. Potentially resectable
indicates that a reduction in tumor size due to chemotherapy could render the tumors
resectable.

Exclusion Criteria:

- Inability to cooperate for an MR exam.

- Contraindication to MR:

- Pacemaker

- Aneurysmal clips

- Any ferrous metallic implants which could be deflected by the magnet

- Metal implants in field of view which could distort the images and spectroscopy
data

- Pregnant women

- Age and mental status wherein he/she is unable to cooperate for MR study

- Patients who are considered to have unresectable hepatic metastases will be excluded.
Hepatic metastases are considered unresectable if their removal would leave behind
insufficient liver parenchyma for subsequent regeneration and survival. In addition,
hepatic metastases are considered unresectable if their removal would be expected to
leave behind residual disease (positive margins). Also, patients are considered
unresectable if they have any comorbid conditions which would jeopardize successful
recovery from hepatic resection.