Randomised, Placebo Controlled, Single-center, Double-blind Clinical Trial to Investigate Efficacy and Safety of Aprepitant Combined With Kevatril and Dexamethasone Versus Placebo Combined With Kevatril and Dexamethasone in Prevention of Acute and Delayed High-dose Chemotherapy-induced Nausea and Vomiting in Subjects With Multiple Myeloma Receiving an Autologous Peripheral Blood Stemcell Transplantation.
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
Overall complete response (no emesis and no rescue therapy)
During and post chemotherapy (0-120 h)
Gerlinde Egerer, MD
University Hospital of Heidelberg; Im Neuenheimer Feld 410; 69120 Heidelberg/ Germany
Germany: Federal Institute for Drugs and Medical Devices