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Does Acupressure Help Reduce Nausea and Vomiting in Palliative Care Patients? Formal Study

18 Years
Open (Enrolling)
Nausea, Vomiting

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Trial Information

Does Acupressure Help Reduce Nausea and Vomiting in Palliative Care Patients? Formal Study

Terminally ill hospice in-patients suffering with nausea will be randomized to active or
placebo acupressure bands. The study will last 3 days and they will be allowed to continue
regular or have PRN anti-emetics during the study.

Assessors and patients will both be blinded to whether they patients are receiving active or
placebo bands.

Inclusion Criteria:

1. Have a diagnosis of advanced cancer with an estimated prognosis of less than 1 year
but more than 3 days.

2. Describe their nausea as at least moderate on a Likert scale OR at have had at least
one vomit per day for the last three days.

3. Have an underlying cause for their nausea which is thought to be irreversible OR the
patient has made an autonomous choice not to proceed with treatment for any
potentially reversible cause (for example surgery for obstruction or drainage of

4. Can be male or female patients but must be over the age of 18.

5. Have signed a consent form prior to entering the study.

6. If patients are taking corticosteroids the dosage should be stable for 3 days before
and during the trial.

7. Be thought to be well enough to complete the 3 day trial.

Exclusion criteria:

1. Arm lymphoedema.

2. Weakness, fatigue or confusion sufficient that patient is unable to take part.

3. Previous history of acupuncture/acupressure for nausea or vomiting, or history of use
of acupressure by a close relative.

4. History of Parkinsonism or Parkinsonism on examination.

5. Patients will not be enrolled if they are sharing a room with another patient taking
part in the study.

6. Patients who are unable to read or comprehend the questionnaire or Visual Analogue

Type of Study:


Study Design:

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment

Outcome Measure:

Number of PRN Doses of anti-emetics needed

Outcome Time Frame:

3 days

Safety Issue:


Principal Investigator

Paul Perkins, MB Bch MRCP

Investigator Role:

Study Director

Investigator Affiliation:

Sue Ryder Care Leckhampton Court Hospice


United Kingdom: Medicines and Healthcare Products Regulatory Agency

Study ID:




Start Date:

July 2010

Completion Date:

July 2015

Related Keywords:

  • Nausea
  • Vomiting
  • Nausea
  • Vomiting
  • Emesis
  • Palliative
  • Terminal
  • Cancer
  • Nausea
  • Vomiting