Trial Information
A Randomized Control Trial of Intravitreal Ranibizumab (Lucentis) for the Prevention of Radiation Maculopathy Following Plaque Radiotherapy for Choroidal Melanoma
Inclusion Criteria:
- Age >18 years
- new diagnosis of choroidal melanoma
- scheduled for plaque radiotherapy at Wills Eye Health System
Exclusion Criteria:
- Pre-existing retinal disorders (i.e. age-related macular degeneration, diabetic
maculopathy, retinal vascular occlusion, macular hole, surface wrinkling retinopathy)
- prior retinal detachment
- media opacities precluding accurate OCT imaging
- history of glaucoma
- pregnancy
- age <18 years.
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
Outcome Measure:
Presence or absence of optical coherence (OCT) evidence of macular edema.
Outcome Time Frame:
4 months
Principal Investigator
Carol L Shields, MD
Investigator Role:
Principal Investigator
Investigator Affiliation:
Wills Eye Institute
Authority:
United States: Institutional Review Board
Study ID:
07-816
NCT ID:
NCT00540930
Start Date:
April 2007
Completion Date:
April 2009
Related Keywords:
- Uveal Melanoma
- Radiation Retinopathy
- Radiation Maculopathy
- Melanoma
- Retinal Diseases
- Uveal Neoplasms
Name | Location |
Wills Eye Institute |
Philadelphia, Pennsylvania 19107 |