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Vibration Response Imaging (VRI) in Patients That Are Candidates for Undergoing Pulmonary Operation Procedure

18 Years
80 Years
Not Enrolling
Emphysema, Cancer

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Trial Information

Vibration Response Imaging (VRI) in Patients That Are Candidates for Undergoing Pulmonary Operation Procedure

Pre lung operation candidates for procedures such as lung volume reduction surgery (LVRS),
lung resection, bullectomy and lung transplant are frequently evaluated for differential
lung function by a semi quantitative lung scintigraphy. VRI may offer the same differential
lung function information for the physician without the risks, time and patient discomfort
of lung scintigraphy in the treating physician office.

Moreover, VRI may provide a safe, quick and simple method to measure "split function" in
lung cancer patients who are candidates for lung surgery. Thus eliminating the safety and
complexity issue related with the current ventilation perfusion "split function" methods.

In addition the VRI may aid in achieving the goal of developing strategies to reduce risk
and maximize the number of patients that can benefit from surgical therapy.

Inclusion Criteria:

1. Able and willing to read, understand, and provide written informed consent;

2. Male or female in the age range of 18-80 years;

3. Patients who were referred to perform perfusion scan for pre lung surgery evaluation
such as LVRS, thoracotomy, bullectomy and lobectomy.

4. Body mass index (BMI) > 21.

Exclusion Criteria:

1. Chest wall deformation;

2. Spine deformation (including scoliosis);

3. Hirsutism;

4. Potentially contagious skin lesion on the back;

5. Skin lesion that would interfere with sensor placement; (Keloids)

6. Cardiac pacemaker or implantable defibrillator;

Type of Study:


Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Principal Investigator

Atul C. Mehta, M.D

Investigator Role:

Principal Investigator

Investigator Affiliation:

The Cleveland Clinic


United States: Institutional Review Board

Study ID:




Start Date:

September 2007

Completion Date:

July 2008

Related Keywords:

  • Emphysema
  • Cancer
  • Emphysema
  • Pulmonary Emphysema



Cleveland ClinicCleveland, Ohio  44195