Preoperative Hepatic Arterial Infusion Chemotherapy in Patients Undergoing Liver Resection for Colorectal Liver Metastases
18 Years
90 Years
Both
Colorectal Liver Metastases
Trial Information
Preoperative Hepatic Arterial Infusion Chemotherapy in Patients Undergoing Liver Resection for Colorectal Liver Metastases
Between 1995 and 2004, 239 patients with isolated colorectal liver metastases received HAI
chemotherapy with neoadjuvant intent. Fifty of these patients underwent subsequent curative
liver resection (HAI group).
Postoperative morbidity, liver function tests, and long term outcomes were evaluated.
Adverse events related to HAI chemotherapy were also evaluated.
Inclusion Criteria:
- Unresectable liver metastases
- Potentially resectable liver metastases
Exclusion Criteria:
- Extrahepatic disease
Type of Study:
Observational
Study Design:
Observational Model: Defined Population, Observational Model: Natural History, Time Perspective: Longitudinal, Time Perspective: Retrospective
Principal Investigator
Luca Aldrighetti, M.D, PhD
Investigator Role:
Principal Investigator
Investigator Affiliation:
Department of Surgery - Liver Unit, Scientific Institute San Raffaele,
Authority:
Italy: Istituto Superiore di SanitÃ
Study ID:
Neoadjuvant HAIC
NCT ID:
NCT00522509
Start Date:
December 1995
Completion Date:
Related Keywords:
- Colorectal Liver Metastases
- Neoplasm Metastasis
- Liver Neoplasms
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