Inclusion Criteria:

- Have non-infectious monoarthritis of the knee and with inadequate response to IA
injection of corticosteroids, at least 3 months before enrollment.

or

- Have oligo or polyarthritis controlled by disease modifying agents (DMARDs) but with
residual 1-2 inflamed joints, one of which is a knee with inadequate response to IA
injection of corticosteroids within 3 months

- Have negative PPD skin test.

- Have no evidence of TB on chest x-ray.

- Be negative for HBsAg and HCV.

- No evidence of infectious arthritis

Exclusion Criteria:

- Known allergy to infliximab.

- Known allergy to lidocaine.

- Pregnant.

- Female patients with childbearing potential who do not practice effective methods of
contraception.

- Suffer from a chronic infection.

- On systemic anti TNF-α or other biologic agents