Trial Information

Etiology of Multiple Myeloma: A Case-Control Study

Informed Consent For Control Subjects:

In this study, researchers are trying to learn about factors that may be associated with
Multiple Myeloma (MM).

For this study, you will be asked to complete a questionnaire. The questionnaire asks
questions about your demographics (for example, age and sex), any chemicals you may have
been exposed to, your medical history, family history of cancer, your diet, and your history
of smoking and/or alcohol use. It should take around 30-40 minutes to complete the
questionnaire.

Blood (about 2-3 tablespoons) will be drawn. You will spit into a collection container in
order to provide a sample of your saliva. The blood and saliva samples will be used for
special tests to look for any biological factors associated with MM.

If you live in Houston or the surrounding area, study personnel can arrange to collect the
samples at the time and place of your convenience. If you do not live in the Houston area,
sample collection instructions and supplies will be mailed to you. The blood sample may be
drawn at your doctor's office, or at a clinic or hospital of your choice. No travel to M.
D. Anderson will be required.

You will be considered off-study after the data that is collected has been processed.

This is an investigational study. Up to 500 participants will take part in this study. All
will be enrolled at M. D. Anderson.

Informed Consent for Patients:

In this study, researchers are trying to learn about factors that may be associated with
Multiple Myeloma (MM).

For this study, you will be asked to complete a questionnaire. The questionnaire asks
questions about your demographics (for example, age and sex), any chemicals you may have
been exposed to, your medical history, family history of cancer, your diet, and your history
of smoking and/or alcohol use. It should take around 30-40 minutes to complete the
questionnaire.

Blood (about 2-3 tablespoons) will be drawn. You will spit into a collection container in
order to provide a sample of your saliva. The blood and saliva samples will be used for
special tests to look for any biological factors associated with MM.

If you live in Houston or the surrounding area, study personnel can arrange to collect the
samples at the time and place of your convenience. If you do not live in the Houston area,
sample collection instructions and supplies will be mailed to you. The blood sample may be
drawn at your doctor's office, or at a clinic or hospital of your choice. No travel to M.
D. Anderson will be required.

Neither you nor your doctor will receive the results of these tests, and they will not be
put in your medical record.

You will be considered off study after the data that is collected has been processed.

This is an investigational study. Up to 500 participants will take part in this study. All
will be enrolled at M. D. Anderson.