Inclusion Criteria:

1. Age >= 18.

2. Cancer visible in liver on CT,MR,US or PET scan.

3. Primary cancer in the liver (hepatocellular carcinoma), or metastatic cancer
involving the liver from a primary such as but not limited to lung, breast, colon,
upper GI, neuroendocrine, melanoma.

4. Life expectancy greater than 2 months

5. Performance status of ECOG 2 or better (Ambulatory and capable of all selfcare, but
unable to carry out any work activities. Up and about more than 50% of waking hours.)

6. Patients have tried and/or are aware of all FDA approved therapies for their
condition.

Exclusion Criteria:

1. Vascular shunt that cannot be corrected.

2. Bulky cancer outside of liver. Active cancer within the liver should be a greater
volume than the active cancer outside the liver / in the remainder of body.

3. Pregnancy

4. Hematologic primary such as lymphoma, leukemia, myeloma.

5. Body weight 300 lbs. and above

6. Evidence of portal hypertension, splenomegaly or ascites.