Inclusion Criteria:

1. Histologically documented Cervical Intraepithelial Neoplasia 1, 2 or 3.

2. Nonpregnant, Nonlactating female greater than or equal to 18 years of age, who is
either surgically sterile, postmenopausal (no menses for the previous 12 months), or
practices an effective method of birth control (to be continued throughout the study
period) as determined by the Investigator (eg: oral contraceptives, injectables or
implants, intrauterine device, double-barrier methods). The use of cervical cap or
diaphram is not permitted).

3. Geographically accessible for ongoing follow up and committed to comply with all
visits.

4. Judged to be in good health based upon the results of a medical history, physical
examination, vital signs and laboratory profile.

5. Capable of understanding and complying with the protocol and has signed the informed
consent.

6. Negative for human immunodeficiency virus (HIV)-1, HIV-2, Hepatitis B surface
antigen, and hepatitis C Virus.

Exclusion Criteria:

Prior to Therapy:

1. Prior exposure to HspE7.

2. The subject received immunotherapy (eg, interferons, tumor necrosis factor,
interleukins, or biological response modifiers [GM CSF, G CSF, M CSF]) within 4 weeks
(28 days) prior to study entry.

3. Taken within 7 days or is currently taking selective Cox-2 inhibitors and other
nonsteroidal anti-inflammatory drugs.

4. Received investigational systemic drugs within 4 weeks (28 days) prior to study
entry.

5. Undergoing active treatment of genital warts.

6. Has taken astemizole within 7 days prior to study drug administration.

Disease Status:

1. Has an autoimmune disease that in the opinion of the investigator would compromise
the safety of the subject in this study. Some examples of autoimmune disease that may
be considered exclusionary include rheumatoid arthritis, systematic lupus
erythematosus, and autoimmune thyroiditis.

2. Has a recognized immunodeficiency disease, including cellular immunodeficiencies,
hypogammaglobulinemia, or dysgammaglobulinemia. The subject has hereditary or
congenital immunodeficiencies.

3. Has a positive endocervical curettage at the time of biopsy.

Physiological Functions:

1. Has clinically significant hepatic dysfunction (ie, alanine aminotransferase,
aspartate aminotransferase, or total bilirubin ≥1.5 x upper limit of normal (ULN).

2. Has clinically significant renal dysfunction (ie, serum creatinine ≥1.5 x ULN).

3. Has clinically significant cardiac disease, eg, New York Heart Association classes
III IV, uncontrolled angina, uncontrolled arrhythmia or uncontrolled hypertension, or
myocardial infarction in the previous 6 months as confirmed by an electrocardiogram.

4. Has had a splenectomy.

5. Has an infectious process that in the opinion of the investigator would compromise
the subject's ability to mount an immune response.

6. Has a history of severe allergic reaction to insect bites or stings, or to any
biologic pharmaceutical product, including compounds similar to the test article.

7. Has donated or lost a significant volume of blood or plasma (greater than 450 mL)
within 30 days of the study.

Standard Safety:

1. Is pregnant or breast-feeding, or a woman of childbearing potential unless using
effective contraception as determined by the investigator. Subjects whom the
investigator considers may be at risk of pregnancy will have a pregnancy test
performed per institutional standard.

2. Any other reason that, in the opinion of the investigator, precludes the subject from
participating in the study.

3. Known hypersensitivity reaction to any of the components of study treatments.

4. Known alcohol or drug abuse, as assessed by the investigator.

5. Legal incapacity or limited legal capacity.