A Retrospective Analysis of Neck Dissection Following Complete Response to Chemoradiation in HNSCC
18 Years
80 Years
Both
Head and Neck Cancer
Trial Information
A Retrospective Analysis of Neck Dissection Following Complete Response to Chemoradiation in HNSCC
OBJECTIVES:
- Perform a retrospective analysis, by medical chart review, of patients with primary
squamous cell carcinoma of the head and neck who underwent neck dissection following
complete response to chemoradiotherapy.
- Determine whether the role of a post-chemoradiotherapy neck dissection affects the
outcome of the patient's disease, in terms of overall survival, disease-free survival,
and recurrence rates.
OUTLINE: This is a pilot, retrospective study.
Patients who have undergone neck dissection after achieving a complete clinical and
radiological response to chemoradiotherapy are compared to patients who did not. Data are
gathered by medical chart review.
Inclusion Criteria:
- Diagnosis of primary squamous cell carcinoma of the head and neck at any of the
following sites:
- Oral cavity
- Oropharynx
- Hypopharynx
- Larynx
- Complete response achieved after treatment with chemoradiotherapy
Exclusion Criteria:
- Not specified
PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
Type of Study:
Observational
Study Design:
Observational Model: Case Control, Time Perspective: Retrospective
Outcome Measure:
Overall survival
Outcome Time Frame:
off-study date
Safety Issue:
No
Principal Investigator
Barbara Murphy, MD
Investigator Role:
Study Chair
Investigator Affiliation:
Vanderbilt-Ingram Cancer Center
Authority:
United States: Federal Government
Study ID:
VICC HN 0435
NCT ID:
NCT00483821
Start Date:
May 2004
Completion Date:
November 2009
Related Keywords:
- Head and Neck Cancer
- stage I squamous cell carcinoma of the hypopharynx
- stage II squamous cell carcinoma of the hypopharynx
- stage III squamous cell carcinoma of the hypopharynx
- stage IV squamous cell carcinoma of the hypopharynx
- stage I squamous cell carcinoma of the larynx
- stage II squamous cell carcinoma of the larynx
- stage III squamous cell carcinoma of the larynx
- stage IV squamous cell carcinoma of the larynx
- stage I squamous cell carcinoma of the lip and oral cavity
- stage II squamous cell carcinoma of the lip and oral cavity
- stage III squamous cell carcinoma of the lip and oral cavity
- stage IV squamous cell carcinoma of the lip and oral cavity
- stage I squamous cell carcinoma of the oropharynx
- stage II squamous cell carcinoma of the oropharynx
- stage III squamous cell carcinoma of the oropharynx
- stage IV squamous cell carcinoma of the oropharynx
- stage I verrucous carcinoma of the larynx
- stage II verrucous carcinoma of the larynx
- stage III verrucous carcinoma of the larynx
- stage IV verrucous carcinoma of the larynx
- stage I verrucous carcinoma of the oral cavity
- stage II verrucous carcinoma of the oral cavity
- stage III verrucous carcinoma of the oral cavity
- stage IV verrucous carcinoma of the oral cavity
- Head and Neck Neoplasms
Name | Location |
|---|---|
| Vanderbilt-Ingram Cancer Center | Nashville, Tennessee 37232-6838 |
| Vanderbilt-Ingram Cancer Center - Cool Springs | Nashville, Tennessee 37064 |
| Vanderbilt-Ingram Cancer Center at Franklin | Nashville, Tennessee 37064 |
