Preoperative Treatment With NSAID in Colorectal Cancer Patients in Relationship to Tumor Host Reactions
Study and control patients are randomized to receive preoperative treatment with
indomethacin or celecoxib compared to sham treatment.Tumor biopsies are taken at operation
and used for analyses of tumor immunity and gene expression.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Kent Lundholm, MD, prof
Sweden: The National Board of Health and Welfare