Trial Information

Treatment of Advanced Cancer With Amplitude-modulated Electromagnetic Fields of Low Intensity by Means of an Intrabuccal Probe

Background: In vitro studies suggest that low levels of amplitude-modulated electromagnetic
fields may modify cell growth. We have identified specific frequencies that may block cancer
cell growth. We have developed a portable and programmable device delivering low levels of
amplitude-modulated electromagnetic fields. The device is connected to a spoon-like coupler,
which is placed in the patient's mouth during treatment.

Methods: We will conducted a feasibility study consisting of three daily treatments. All
patients with advanced solid tumors and measurable disease will be eligible, irrespective of
prior treatments. Patients will be assessed with laboratory exams (complete blood count,
comprehensive profile, tumor markers), imaging studies every other month for the first six
months, every third month thereafter.