Trial Information

Evaluation of the Radionics Body Localizer System and XPLAN/IMRT for Extra-Cranial Sites: A Pilot Study

OBJECTIVES:

- Determine the ability of the Radionics Body System™ to immobilize and re-localize
patients receiving radiotherapy to extra-cranial sites of cancer.

- Determine the accuracy of radiation dose calculations for extra-cranial sites of cancer
when using the XPLAN™-intensity modulated radiation therapy (XPLAN™/IMRT) integrated
software in this system.

OUTLINE: Patients receiving radiotherapy have a Body Localizer cast constructed and undergo
a CT scan while immobilized in the Body Localizer. Patients undergo another CT scan in the
treatment position using the standard alpha cradle. The XPLAN™-intensity modulated radiation
therapy (XPLAN™/IMRT)-generated treatment plan is compared to the standard treatment plan to
verify that the calculated dose is within 2-3 percent of the planned dose using standard
technique. Patients undergo sets of CT scans 3 additional times over the next few weeks for
a total of 8 CT scans Patients may undergo additional CT scans before and after radiotherapy
treatments for a maximum of 5 CT scans per week performed over the course of radiotherapy.

PROJECTED ACCRUAL: Approximately 60 patients will be accrued for this study.