Breast Cancer- Early Detection of Cancer Disease and Pre-Cancer Disease, and in Women That Are at High Risk for Developing Breast Cancer by Identifying Lymphocytes Previously Exposed to Specific Cancer Antigen.
Women carrying benign breast lesions will be further divided and analyzed according to the
Fitzgibbon's risk categories for invasive cancer risk (4). The Fitzgibbon's categories
1. No increased risk group including adenosis (other than sclerotic), duct ectasia
fibroadenoma without complex features,
2. slightly increased risk group (1.5-20 times) which includes fibroadenoma with complex
features, moderate or florid hyperplasia without atypia, sclerosing adenosis,
3. moderately increased risk group (4.0-5.0 times) includes atypical ductal and lobular
4. markedly increased risk group (8.0-10.0 times) which includes ductal and lobular
carcinomas In Situ Following the blood collection, detailed relevant clinical
information of the patient will be registered in a case record form.
The data will include: age, country of birth, last menstrual period, lactation, number of
children, age at first full-term pregnancy, age at onset of menopause, family history,
medication, mammography findings, FNA results, tumor size, histological findings,
biopsies, disease staging, and other relevant clinical information.
2. experiencing menstruation, or
3. under hormonal or drug treatment.